Publications

46. Jagersma J, Pyott SJ, Olivier JDA. Slight and hidden hearing loss differentially affect short- and long-term memory in young rats. Behavioural Pharmacology. In review.

45. Bovee S, Jüchter C, Klump GM, Köppl C, Pyott SJ. Degeneration of the stria vascularis in quiet-aged gerbils: Linking structural and cellular changes to cochlear function. Hear Res. In revision.

44. Short E, ICCARP, Calimport S, Bentley B. Defining an ageing-related pathology, disease or syndrome: International Consensus Statement. GeroScience. 2024. 10.1007/s11357-024-01315-9. doi.org/10.1007/s11357-024-01315-9. [Link]

43. Schubert, NMA, DOJ Reijntjes, M van Tuinen, S Vijayakumar, TAJones, SM Jones, and SJ Pyott. Pathophysiological processes underlying hidden hearing loss revealed in Kcnt1/2 double knockout mice. Aging cell. 2024. e14243. doi.org/10.1111/acel.14243. PMID: 39049179. [Link]

42. Jagersma J, Bakker M, Olivier JDA, and Pyott SJ. Slight and hidden hearing loss in young rats is associated with impaired recognition memory and reduced myelination in the corpus callosum. Behavioral Neuroscience, 2024 Oct 10. doi: 10.1037/bne0000601. [Link]

41. Makani P, Thioux M, Koops EA, Pyott SJ, van Dijk P. Hyperacusis in Tinnitus Individuals Is Associated with Smaller Gray Matter and Volumes in the Supplementary Motor Area Regardless of Hearing Levels. Brain Sciences. 2024; 14(7):726. doi.org/10.3390/brainsci14070726. [Link]

40. Bovee S, Klump GM, Köppl C, Pyott SJ. The Stria Vascularis: Renewed Attention on a Key Player in Age-Related Hearing Loss. Int J Mol Sci. 2024 May 15;25(10). doi: 10.3390/ijms25105391. Review. PubMed PMID: 38791427; PubMed Central PMCID: PMC11121695. [Link]

39. Castaño-González K, Köppl C, Pyott SJ. The crucial role of diverse animal models to investigate cochlear aging and hearing loss. Hear Res. 2024 Apr;445:108989. doi: 10.1016/j.heares.2024.108989. PMID: 38518394. [Link]

38. Bovee S, Klump GM, Pyott SJ, Sielaff C, Köppl C. Cochlear Ribbon Synapses in Aged Gerbils. Int J Mol Sci. 2024 Feb 27;25(5). doi: 10.3390/ijms25052738. PubMed PMID: 38473985; PubMed Central PMCID: PMC10931817. [Link]

37. Pyott SJ, Pavlinkova G, Yamoah EN, Fritzsch B. Harmony in the Molecular Orchestra of Hearing: Developmental Mechanisms from the Ear to the Brain. Annu Rev Neurosci. 2024 Feb 15;. doi: 10.1146/annurev-neuro-081423-093942. [Epub ahead of print] Review. PubMed PMID: 38360566. [Link]

36. Paplou VG, Schubert NMA, van Tuinen M, Vijayakumar S, Pyott SJ. Functional, Morphological and Molecular Changes Reveal the Mechanisms Associated with Age-Related Vestibular Loss. Biomolecules. 2023 Sep 21;13(9). doi: 10.3390/biom13091429. PubMed PMID: 37759828; PubMed Central PMCID: PMC10526133. [Link]

35. Makani P, Koops EA, Pyott SJ, van Dijk P, Thioux M. Hyperacusis is associated with smaller gray matter volumes in the supplementary motor area. Neuroimage Clin. 2023;38:103425. doi: 10.1016/j.nicl.2023.103425. Epub 2023 Apr 29. PubMed PMID: 37137255; PubMed Central PMCID: PMC10176058. [Link]

34. Schubert NMA, Roelofs CG, Free RH, Wiersinga-Post JEC, Pyott SJ. Age-related High-frequency Hearing Loss Is Not Associated With Horizontal Semicircular Canal Function. Ear Hear. 2022 Nov-Dec 01;43(6):1845-1852. doi: 10.1097/AUD.0000000000001252. Epub 2022 Oct 18. PubMed PMID: 35696183; PubMed Central PMCID: PMC9592157. [Link]

33. Makani P, Thioux M, Pyott SJ, van Dijk P. A Combined Image- and Coordinate-Based Meta-Analysis of Whole-Brain Voxel-Based Morphometry Studies Investigating Subjective Tinnitus. Brain Sci. 2022 Sep 3;12(9). doi: 10.3390/brainsci12091192. PubMed PMID: 36138928; PubMed Central PMCID: PMC9496862. [Link]

32. Schubert, NMA, M van Tuinen, and Pyott SJ. (2022). Transcriptome-Guided Identification of Drugs for Repurposing to Treat Age-Related Hearing Loss. Biomolecules. 12(4). [Link]

31. Buffenstein, R, V Amoroso, B Andziak, S Avdieiev, J Azpurua, AJ Barker, NC Bennett, MA Brieno-Enriquez, GN Bronner, C Coen, MA Delaney, CM Dengler-Crish, YH Edrey, CG Faulkes, D Frankel, G Friedlander, PA Gibney, V Gorbunova, C Hine, MM Holmes, JUM Jarvis, Y Kawamura, N Kutsukake, C Kenyon, WT Khaled, T Kikusui, J Kissil, S Lagestee, J Larson, A Lauer, LA Lavrenchenko, A Lee, JB Levitt, GR Lewin, KN Lewis Hardell, TD Lin, MJ Mason, D McCloskey, M McMahon, K Miura, K Mogi, V Narayan, TP O’Connor, K Okanoya, MJ O’Riain, TJ Park, NJ Place, K Podshivalova, ME Pamenter, SJ Pyott, J Reznick, JG Ruby, AB Salmon, J Santos-Sacchi, DK Sarko, A Seluanov, A Shepard, M Smith, KB Storey, X Tian, EN Vice, M Viltard, A Watarai, E Wywial, M Yamakawa, ED Zemlemerova, M Zions, and ESJ Smith. (2022) The naked truth: a comprehensive clarification and classification of current ‘myths’ in naked mole-rat biology. Biol Rev Camb Philos Soc, 2022. 97(1): p. 115-140. [Link]

30. Schubert, NMA, JGM Rosmalen, P van Dijk, and Pyott SJ. (2022). A retrospective cross-sectional study on tinnitus prevalence and disease associations in the Dutch population-based cohort Lifelines. Hear Res. 411: p. 108355. [Link]

29. Paplou, V, NMA Schubert, and Pyott SJ (2021) Age-Related Changes in the Cochlea and Vestibule: Shared Patterns and Processes. Front Neurosci. 15: p. 680856. [Link]

28. Reijntjes, DOJ, JL Breitzler, D Persic, and Pyott SJ. (2021) Preparation of the intact rodent organ of Corti for RNAscope and immunolabeling, confocal microscopy, and quantitative analysis. STAR Protoc. 2(2): p. 100544. [Link]

27. Greguske EA, Llorens J, Pyott SJ. (2021) Assessment of cochlear toxicity in response to chronic 3,3′-iminodipropionitrile in mice reveals early and reversible functional loss that precedes overt histopathology. Arch Toxicol. 95(3):1003-1021. [PDF]

26. Pyott, SJ*, M van Tuinen M, LA Screven, KM Schrode, J-P Bai, CM Barone, SD Price, A Lysakowski, M Sanderford, S Kumar, J Santos-Sacci, AM Lauer, and TJ Park. (2020) Functional, morphological, and evolutionary characterization of hearing in subterranean, eusocial African mole-rats. Curr Biol. S0960-9822(20)31189-1. [*Lead/senior author] [PDF]

25. Persic, D, ME Thomas, V Pelekanos, DK Ryugo, AE Takesian, K Krumbholz, and SJ Pyott. (2020) Regulation of auditory plasticity during critical periods and following hearing loss. Hear Res. 397:107976. [PDF]

24. Reijntjes, DOJ, C Köppl, and SJ Pyott. (2020) Volume gradients in inner hair cell-auditory nerve fiber pre- and postsynaptic proteins differ across mouse strains. Hear Res. 390:107933. [PDF]

23. Lingle CJ, Martinez-Espinosa PL, Yang-Hood A, Boero LE, Payne S, Persic D, V-Ghaffari B, Xiao M, Zhou Y, Xia XM, Pyott SJ, Rutherford MA. (2019) LRRC52 regulates BK channel function and localization in mouse cochlear inner hair cells. Proc Natl Acad Sci U S A. 116(37):18397-18403. [PDF]

22. Barone CM, Douma S, Reijntjes DOJ, Browe BM, Köppl C, Klump G, Park TJ, Pyott SJ. (2019) Altered cochlear innervation in developing and mature naked and Damaraland mole rats. J Comp Neurol. 527(14):2302-2316. [PDF]

21. Reijntjes DOJ, Lee JH, Park S, Schubert NMA, van Tuinen M, Vijayakumar S, Jones TA, Jones SM, Gratton MA, Xia XM, Yamoah EN, Pyott SJ. (2019) Sodium-activated potassium channels shape peripheral auditory function and activity of the primary auditory neurons in mice. Sci Rep. 9(1):2573. [PDF]

20. Reijntjes DOJ, Schubert NMA, Pietrus-Rajman A, van Dijk P, Pyott SJ. (2018) Changes in spontaneous movement in response to silent gaps are not robust enough to indicate the perception of tinnitus in mice. PLoS One. 13(8):e0202882. [PDF]

19. Ye Z, Goutman JD, Pyott SJ, Glowatzki E. (2017) mGluR1 enhances efferent inhibition of inner hair cells in the developing rat cochlea. J Physiol. 595(11):3483-3495. [PDF]

18. Hoadley KD, Vize PD, Pyott SJ. (2016) Current Understanding of the Circadian Clock Within Cnidaria.  The Cnidaria, Past, Present and Future. 511-520. [PDF]

17. Goutman JD, Pyott SJ. (2016) Whole-Cell Patch-Clamp Recording of Mouse and Rat Inner Hair Cells in the Intact Organ of Corti. Methods Mol Biol. 1427:471-85. [PDF]

16. Pyott SJ, Duncan RK. (2016) BK Channels in the Vertebrate Inner Ear. Int Rev Neurobiol. 128:369-99. [PDF]

15. Reijntjes DO, Pyott SJ. (2016) The afferent signaling complex: Regulation of type I spiral ganglion neuron responses in the auditory periphery. Hear Res. 336:1-16. [PDF]

14. Braude JP, Vijayakumar S, Baumgarner K, Laurine R, Jones TA, Jones SM, Pyott SJ. (2015) Deletion of Shank1 has minimal effects on the molecular composition and function of glutamatergic afferent postsynapses in the mouse inner ear. Hear Res. 321:52-64. [PDF]

13. Rohmann KN, Wersinger E, Braude JP, Pyott SJ, Fuchs PA. (2015) Activation of BK and SK channels by efferent synapses on outer hair cells in high frequency regions of the rodent cochlea. J Neurosci. 35:1821-30. [PDF]

12. Sadeghi SG, Pyott SJ, Zhou Y, Glowatzki E. (2014) Glutamatergic signaling at the vestibular hair cell calyx synapse. J. Neurosci. 34:14536-50. [PDF]

11. Schuth O, McLean WJ, Eatock RA, Pyott, SJ. (2014) Distribution of Na,K-ATPase α Subunits in Rat Vestibular Sensory Epithelia. J Assoc Res Otolaryngol. 15:739-54. [PDF]

10. Maison SF, Pyott SJ, Meredith AL, Liberman, MC. (2013) Olivocochlear suppression of outer hair cells in vivo: combined action of BK and SK2 channels throughout the cochlea. J Neurophys. 109:1525-34. [PDF]

9. Hoadley KD, Szmant AM, Pyott SJ. (2011) Circadian clock gene expression in the coral Favia fragum over diel and lunar reproductive cycles. PLoS One. 6(5):e19755. [PDF]

8. Wersinger E, McLean WJ, Fuchs PA, Pyott SJ. (2010) BK channels mediate cholinergic inhibition of high frequency cochlear hair cells. PlosOne. 5(11): [PDF]

7. de San Martín JV, Pyott S, Ballestero J, Katz E. (2010) Ca2+ and Ca2+-activated K+ channels that support and modulate transmitter release at the olivocochlear efferent-inner hair cell synapse. J Neurosci. 30:12157-67. [PDF]

6. McLean WJ, Smith AK, Glowatzki E, Pyott SJ. (2009) Distribution of the Na,K-ATPase α subunit in the rat spiral ganglion and organ of Corti. J Assoc Res Otolaryngol. 10:37-49. [PDF]

5. Pyott SJ, Meredith AL, Fodor AA, Vazquez AE, Yamoah EN, Aldrich RW. (2006) Normal cochlear function in mice lacking the BK channel a, b1, or b4 subunits. J Biol Chem 282:3312-3324. [PDF]

4. Pyott SJ, Glowatzki E, Trimmer JS, Aldrich RW. (2004) Extrasynaptic Localization of Inactivating Calcium-Activated Potassium Channels in Mouse Inner Hair Cells. J Neurosci 24:9469-9474. [PDF]

3. Pyott SJ, Rosenmund C. (2002) The effects of temperature on vesicular supply and release in autaptic cultures of rat and mouse hippocampal neurons. J Physiol 539:523–535. [PDF]

2. Rhee JS*, Betz A*, Pyott SJ*, Reim K, Varoqueaux F, Augustin I, Hesse D, Südhof TC, Takahashi M, Rosenmund C, Brose N. (2002) Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by munc13s and not by PKCs. Cell 108:121–133. [*Equal contributors] [PDF]

1. Colliver TL, Pyott SJ, Achalabun MA, Ewing AG (2000) VMAT mediated changes in quantal size and vesicular volume. J Neurosci 20:5276–5282. [PDF]